The process by which the placenta uses the neonatal Fc receptorFc receptor A specialized transport protein. In FNAIT, it carries maternal antiplatelet IgG antibodies across the placenta into the fetus, which destroys the fetus's platelets. (FcRnFc receptor A specialized transport protein. In FNAIT, it carries maternal antiplatelet IgG antibodies across the placenta into the fetus, which destroys the fetus's platelets.) to transfer maternal IgG antibodies to provide the fetus with passive immunity. In FNAITFetal and neonatal alloimmune thrombocytopenia A rare condition in which a mother’s immune system attacks fetal platelets, leading to dangerously low platelet levels before and/or after birth., this process misroutes harmful anti-platelet alloantibodies into the fetal circulation.
