Rosemary

All articles by Rosemary

• FNAIT diagnosis after birth: Your ultimate guide

  Learn more about FNAIT diagnosis after birth, including common symptoms and tests used to confirm the diagnosis.

• Prenatal FNAIT diagnosis: Your ultimate guide

  Learn more about how FNAIT is diagnosed during pregnancy, the types of tests involved and what you can expect throughout the process.

• Washed maternal platelets

  Platelets collected from the mother and washed to remove plasma. Often used for transfusion in newborns when matched donor platelets are unavailable.

• Thrombocytopenia

  A platelet countPlatelet count A measure of how many platelets are in the blood. FNAIT is characterized by severely reduced counts in a fetus or newborn. that is lower than normal.

• Severe thrombocytopenia

  A dangerously low platelet countPlatelet count A measure of how many platelets are in the blood. FNAIT is characterized by severely reduced counts in a fetus or newborn., typically below 50,000 platelets per microliter and sometimes far lower in FNAITFetal and neonatal alloimmune thrombocytopenia A rare condition in which a mother’s immune system attacks fetal […]

• Sensitization

  Another term for alloimmunizationAlloimmunization The process by which the mother becomes sensitized to fetal platelet antigens and begins producing alloantibodies. This is what causes FNAIT., this refers to the immune system’s response to foreign platelet antigens.

• Reference platelets

  Specially matched donor platelets, often HPAHuman platelet antigen Proteins found on the surface of platelets. Incompatibility between maternal and fetal human platelet antigens can trigger FNAIT.-negative, used for transfusions in newborns with FNAITFetal and neonatal alloimmune thrombocytopenia A rare condition in which a mother’s immune system attacks fetal platelets, leading to dangerously low platelet levels […]

• Recurrence risk

  The chance that FNAITFetal and neonatal alloimmune thrombocytopenia A rare condition in which a mother’s immune system attacks fetal platelets, leading to dangerously low platelet levels before and/or after birth. will affect future pregnancies. Once a woman is sensitized, the risk of FNAIT in future pregnancies is high.

• Paternal genotyping

  Testing the father’s blood to determine which HPAs may have been passed to the fetus.

• Platelet transfusion

  A treatment for newborns with very low platelet counts that ideally uses HPAHuman platelet antigen Proteins found on the surface of platelets. Incompatibility between maternal and fetal human platelet antigens can trigger FNAIT.-compatible or washed maternal plateletsWashed maternal platelets Platelets collected from the mother and washed to remove plasma. Often used for transfusion in newborns […]