Ariana Boswell

All articles by Ariana Boswell

• Understanding platelet match scarcity & what it means for newborn care

  While matched platelets are preferred for individuals with FNAIT, unmatched ones can also be used when necessary.

• Demand on the rise for matched platelet transfusions in Canada

  The HLA/HPA Platelet Program at Canadian Blood Services, which serves patients with FNAIT, has seen an increased need for matched platelets.

• Study pinpoints anti-HPA-1a antibodies that may raise FNAIT risk

  Certain anti-HPA-1a antibodies can cause platelet aggregation through the FcγRIIa receptor, a mechanism that may contribute to FNAIT.

• The role of the spleen in FNAIT

  Learn more about the role and function of the spleen, which is a major site of platelet destruction, in FNAIT.

• Researchers pinpoint molecule that may worsen brain bleed injuries

  Researchers developed a three-dimensional model to study the mechanisms behind intraventricular hemorrhage.

• Case report: Failed platelet transfusion due to HLA, HPA antibodies

  A woman who experienced a miscarriage did not respond to several platelet transfusions due to the presence of anti-platelet antibodies.

• Patients describe emotional burden of FNAIT diagnosis and care

  Interviews of patients affected by FNAIT revealed diagnostic challenges and strained relationships with healthcare providers.

• Study: The role of anti-HLA antibodies in FNAIT remains unclear

  A study found that anti-HLA antibodies can trigger mild thrombocytopenia in mice, but their ability to cause FNAIT is uncertain.

• How platelet transfusions for FNAIT differ from other disorders

  Find out how platelet transfusions for FNAIT are different from those used to treat other bleeding disorders.

• New method may help predict platelet transfusion risk in infants

  Researchers developed a statistical model that could help clinicians make platelet transfusion decisions for infants with thrombocytopenia.