Megan Garlapow, PhD

All articles by Megan Garlapow, PhD

• Non-invasive testing could help predict infant blood groups

  Non-invasive prenatal testing has enhanced safety and accuracy for alloimmunized pregnancies, including in those with FNAIT and HDFN.

• New hemolysis tests could improve safety of IVIG treatments

  In a recent study, functional assays more accurately assessed hemolysis risks in IVIG products, which are a frontline treatment in FNAIT.

• New therapy shows early promise in preventing FNAIT

  Preclinical data from Rallybio suggested that RLYB212 may prevent fetal and neonatal allo-immune thrombocytopenia in high-risk pregnancies.

• Study: Optimizing platelet transfusions improved preterm infant outcomes

  In a recent study, a 10 mL/kg standardized dose for platelet transfusions reduced neonatal platelet exposure without increasing risks.

• Study: HLA-matched platelet transfusions showed highest success rate

  Comprehensive care strategies could improve outcomes for patients experiencing platelet transfusion refractoriness.

• Utilizing immune cell ratios could improve pregnancy outcomes

  A specific immune cell ratio may be able to predict pregnancy outcomes in women with recurrent pregnancy loss.